Skin-B ®

Filling and modelling solution based on hyaluronic acid.

Registered Trademark


Skin-B is a filling and modelling solution of the dermal matrix based on hyaluronic acid. Class III medical device with CE mark issued by the National Institute of Health and containing: fragments of hyaluronic acid (20-38 monomers), amino acids, buffer system based on bicarbonate.

Patented Product

How to use

Inject an appropriate quantity of the solution into the surface layer of the dermis in the following points: glabella, nasolabial folds, cheekbones, lower corner of the mouth and submental area.


One session every 7 days for 4 times. Then one session every 15 days for 2 times; further a maintenance treatment every 30 days.

Principle of method

CD44 of the fibroblasts are activated and the cells in the surrounding area are provided with the necessary principles for the build-up of collagen, elastin and glycosaminoglycans. Biological optimization of skin condition will be obtained. In addition, acid buffering of the matrix maintains the sol status of colloidal solution and facilitates the metabolic exchanges.


At present the most commonly performed medical procedure for improving skin physiology is the bio-stimulation that provides fibroblast activation for the build- up of new matrix components and the normalization of the colloidal state of the matrix.
The Medical Device used for this purpose contains: fragments of hyaluronic acid (20-38 monomers) capable of activating CD44 of
fibroblast / amino acid precursors for collagen, elastin and glycosaminoglycans / buffer system based on bicarbonate.
The product should be administered intradermally according to the primary mesotherapy injecting technique.